Pharmaceutical Grade Male Sex Hormones Estradiol Cypionate 99% Min CAS 313-06-4

Pharmaceutical Grade Sex Hormone Estradiol Cypionate 99%min CAS 313-06-4

 

Quick Details:

 

• Estradiol Cypionate
• Alias:Depofemin
• Purity : 99%min
• CAS Registry Number: 313-06-4
• Einecs No: 206-237-8
• Molecular formula: C26H36O3
• Molecular weight:396.56
• Grade : Pharmaceutical Grade
• Storage: Shading, confined preservation
• Usage : pharmaceutical material, etc

 

 

Description:

 

1. Estradiol is a sex hormone that is present in both males and females, and is the most important form of

 

estrogen in humans. In women, it plays a key role in the development and functioning of the reproductive

 

system, as well as in the growth of certain bones. It also governs the distribution of body fat in women and

 

is the main hormone responsible for the fact that women are shorter than men, on average. Both the

 

ovaries and the adrenal glands produce it.

 

2. The menstrual cycle in women involves predictable variations in the levels of several hormones, with

 

estradiol being one of them. It is involved in the ovulation process and prepares the inner lining of the

 

uterus for implantation, should the egg be fertilized. Certain tests done on baboons and other primates

 

have indicated that his hormone also plays a continual role in maintaining a pregnancy, helping it to last

 

for the full gestation period.

 

3. As a sex hormone, it also triggers many of the developments of the reproductive system that begin in

 

puberty. It is present throughout the reproductive years, and declines during and after menopause. This

 

decline is precisely what causes many of the symptoms of menopause, such as hot flashes and night

 

sweats, vaginal dryness, and the loss of bone mass that may lead to osteoporosis.

 

 

Specifications :

 

Product name	Estradiol
Appearance	White crystalline powder
Characteristics	White or creamy white, crystalline powder	conform
Melting point	176-180 °C	178~ 179°C
Water	≤3.5%	pass
Assay	97 .0~ 103.0%	99.3%
Loss on drying	≤0.5%	0.1%
Related substances	total impurities ≤1.0%	Pass
	any individual impurity ≤0.5%	Pass
Residual solvents	ethanol ≤0.5%	Pass

 

Applications:

 

1. Depofemin is a long-effect estrogen. Compared with Estradiol Valerate, it has stronger and

 

longer effects. It is used for the treatment of ovarian insufficiency, amenorrhea, menopausal syndrome,

 

senile vaginitis, and prostatic cancer. The compound of Depofemin and Medroxyprogesterone 17-acetate

 

is a one-month long-term contraceptive injection.

 

2. Estradiol cypionate (INN, USAN; DepoEstradiol, Depofemin, Estradep, many others), or estradiol

 

cipionate, is a synthetic ester, specifically the 3cyclopentylpropanoyl ester, of the natural estrogen,

 

estradiol. It was first introduced in 1952 by Upjohn in the United States,and has been in widespread use

 

since. Estradiol cypionate is absorbed more slowly than estradiol itself, and for that reason, it can be

 

administered less often.

 

 

Items	Standard	Results
Assay by HPLC:	98%	99.37%
Appearance:	White fine powder	Complies
Odor & taste:	Slight bitter	Complies
Mesh size:	100% pass 80mesh	Complies
Solubility:	Soluble in water	Complies
Loss on drying:	≤2.0%	1.15%
Heavy metals PPM:	<30ppm	Complies
Microbiology: Total Plate Count: Yeast & Mold: E.Coli: S. Aureus: Salmonella:	<1000cfu/g <100cfu/g Negative Negative Negative	800cfu/g 90cfu/g Complies Complies Complies
Conclusion:	Conform with USP35 standard

 

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Pharmaceutical Grade Male Sex Hormones Estradiol Cypionate 99% Min CAS 313-06-4 Images