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Etizolam Rcnet Chemical White Powder CAS 40054 69 1 Formula C17H15ClN4S Purity
- etizolam
CAS 40054-69-1
- China
- 10g
- Negotiable
- 1kg/Aluminum foil bag
- 3-5 days after received your deposit
- MoneyGram, Western Union, D/P, T/T
- 1000kg/month
-
Zhongjian chemicals Co.,Ltd2020-07-10 09:46:19
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Product Details
| Appearance: | powder | Purity: | 99% | Production Capacity: | 1000kg/month |
| color: | white | DeliveryTime: | 3-5 days after received your deposit | Packing: | Safe discreet packages through Customers |
| Package: | 1kg/Aluminum foil bag |
Product Description
Tolerance, dependence and withdrawal
Abrupt or rapid discontinuation from etizolam, as with benzodiazepines, may result in the appearance
of the benzodiazepine withdrawal syndrome, including rebound insomnia.Neuroleptic malignant
syndrome, a rare event in benzodiazepine withdrawal, has been documented in a case of abrupt
withdrawal from etizolam. This is particularly relevant given etizolams short half life relative to
benzodiazepines such as diazepam resulting in a more rapid drug level decrease in blood plasma levels.
In a study that compared the effectiveness of etizolam, alprazolam, and bromazepam for the
treatment of generalized anxiety disorder, all three drugs retained their effectiveness over 2 weeks,
but etizolam became more effective from 2 weeks to 4 weeks, a type of reverse tolerance.[13]
Administering .5 mg etizolam twice daily did not induce cognitive deficits over 3 weeks when
compared to placebo.
When multiple doses of etizolam, or lorazepam, were administered to rat neurons, lorazepam caused
downregulation of alpha-1 benzodiazepine binding sites (tolerance/dependence), while etizolam caused
an increase in alpha-2 benzodiazepine binding sites (reverse tolerance to anti-anxiety effects)
Tolerance to the anticonvulsant effects of lorazepam was observed, but no significant tolerance to
the anticonvulsant effects of etizolam was observed. Etizolam therefore has a reduced liability to
induce tolerance, and dependence, compared with classic benzodiazepines.
Pharmacology
Etizolam, a thienodiazepine derivative, is absorbed fairly rapidly, with peak plasma levels achieved between
30 minutes and 2 hours. It has a mean elimination half life of about 3.5 hours. Etizolam possesses
potent hypnotic properties,and is comparable with other short-acting benzodiazepines.Etizolam acts as a
full agonist at the benzodiazepine receptor to produce its range of therapeutic and adverse effects.
According to the Italian P.I. etizolam belongs to a new class of diazepines,
thienotriazolodiazepines. This new class is easily oxidized, rapidly metabolized, and has a lower risk of
accumulation, even after prolonged treatment. Etizolam has an anxiolytic action about 6 times greater than
that of diazepam. Etizolam produces, especially at higher dosages, a reduction in time taken to fall asleep,
an increase in total sleep time, and a reduction in the number of awakenings. During tests, there were no
substantial changes in deep sleep; however, it may reduce REM sleep. In EEG tests of healthy volunteers,
etizolam showed some similar characteristics to tricyclic antidepressants.
1. Quick Details
Cas no: 52170-72-6
Molecular Formula: C17H15N4OSCl
Purity:99.5%
Appearance: White or Similar crystalline powder
Storage: store in dry and cool place.
2. IntroductionsLots of customers admitted its similarity to Xana as Etizolam is medicine to benzodiazepines. Users also mentioned similar effects to tricyclic antidepressants.
The process of absorption is really fast and it takes from half of an hour to two hours. It raises the level of prolactin in blood. The duration of the whole process is about eight hours.
Our company can offer you to buy Etizolam in powder form.
Etizolam side effects haven’t been studied yet, but thanks to a large number of consumers it is possible to identify such effects as euphoria, which could be observed in most users, and elimination of anxiety. Sedation and suppression of data processing are also in the list of side effects.
Lots of consumers stated that they didn’t have any negative effects when taking a light dose. And taking a strong dose it’s possible to experience memory loses. After trying various bath salts, consumers have no doubts with the right choice to choose exactly this one for their experiments
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Etizolam Rcnet Chemical White Powder CAS 40054 69 1 Formula C17H15ClN4S Purity Images |
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