Competitive price 99.8% Purity Research Chemicals Powder 4-CN- BINACA -ADB

99.8% Purity Research Chemicals Powder 4-CN- BINACA -ADB Pharmaceutical Grade

• CUMYL-4CN-BINACA(1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide) is a recently introduced indazole-3-carboxamide type synthetic cannabinoid (SC) that was detected in herbal incense seized by of the Council of Forensic Medicine Istanbul Narcotics Department in May 2016 in Turkey. Recently introduced SCs are not detected in routine toxicological analysis; therefore, analytical methods to measure these compounds are in demand. The present study aims to identify urinary marker metabolites of CUMYL-4CN-BINACA by investigating its metabolism in human liver microsomes and to confirm the results in authentic urine samples (n=80). In this study, 5 μM CUMYL-4CN-BINACA was incubated with HLMs for up to 3 h, and metabolites were identified using liquid chromatography high-resolution mass spectrometry (LC-HRMS). Less than 21% of the CUMYL-4CN-BINACA parent compound remained after 3 h of incubation. We identified 18 metabolites that were formed via monohydroxylation, dealkylation, oxidative decyanation to aldehyde, alcohol and carboxylic acid formation, glucuronidation or reaction combinations. CUMYL-4CN-BINACA N-butanoic acid (M16) was found to be major metabolite in HLMs. In urine samples CUMYL-4CN-BINACA was not detected; CUMYL-4CN-BINACA N-butanoic acid (M16) was major metabolite after β-glucuronidase hydrolysis. Based on these findings, we recommend using M16 (CUMYL-4CN-BINACA N-butanoic acid), M8 and M11 (hydroxylcumyl CUMYL-4CN-BINACA) as urinary marker metabolites to confirm CUMYL-4CN-BINACA intake
  Detection of Metabolites of the New Synthetic Cannabinoid CUMYL-4CN-BINACA in Authentic Urine Samples and Human Liver Microsomes Using High-resolution Mass Spectrometry. Available from

• Details

  1. how is the quality	the qualities of most products are above 99% purity, same are 99.5% purity.
  2, how is the package	foil bag or as customers required.
  3, how is the storage	keep in dry and cool place.
  4, do i need to pay extra for shipping cost	no, our price includes the shipping cost already; you need not pay for any tax and others.
  5, can i order sample to test	yes, you are welcome to order sample before placing bulk order. we will send the sample directly to your door by courier.
  6, minimum quantity	usually our minimum quantity is 50g. but you are welcome to order samples to check the quality and our service.

• Why choose us

1. Rich experience

We specialize in this filed for many years,our steriods and hormones exported to all over the world and established long friendly relations of coroperation with them.

2. Great quality,purity and favorable

Good quality is one of our biggest secert to success;u can get the best quality and service from us.

3. Safest and fastest delivery

We have adequate stock so that we can deliver the products with 24 hours as soon as receiving the payment.Fast and discreet shipment will be arranged to pass customs.

4. Good package

Unique ways to ship 10g to 100kg powders to your destination.We offer melting powder into liquid service and ship the liquid in special bottles.

5. Great after-sales service

Any questions or problems after receiving the product,pls feel free to contact us.Problems would be solved immediately.

2. Order Guide

Q1: Have your Product Quality been Approved by Third Party Lab
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.

Q2: How do you treat quality complaint
A: First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.

Q3: Is there any discount
A: Yes, for larger quantity, we always support with better price.

Q4: How long does it take to the goods arrived
A:It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q5 Do you have any reshipment policy
A: We have good after-sale service and re-shipment policy if the parcel lose.
Our long association with our clients has brought great benefits.
We always take the upmost care in the packaging of our products .
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship.